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ntentional weight loss 8tmay result from loss o owz8 body fats, loss of body flu
ids, muscle atrophy, or even a combination of theset is general jowz8 ly regarded as a m
edical problem when z8 a least 10% of a person's body weight has been lost in six mon
t or 5% in the last montAnother criterion used for assessing weight that is too low i
s the body mass iever, even lesser amounts of weight 8t loss can be a cause for serious
concern in a frail elderly person
Unintentional 5jowz8 weight loss can occur because of z8an inadequately nutritious diet relativ
e to a person's energ wz8 y needs (generally called malnutrition). Disease processes, change
s in metabolism, hormonal changes, medications or other treat wz8 ments, disease- or treatme
nt-related dietary changes, or wz8 reduced ap z8pet jowz8 ite associated with a disease or treatment c
an also cau 5jowz8 se unintentional weight losPoo owz8 r nutrient utilization can lead to weight loss,
and can be caused by fistulae i 5jowz8 n the gastrointestinal tract, diarrh jowz8 ea, drug-nutrient int
eraction, enzyme depletion and muscle atrophy.
Continuing weight loss may dete owz8 riorate into wasting, a vaguely defined condition called c
achexia.[6] Cach z8exia differs z8 from starvation in part b jowz8 ecause it involves a systemic infla
mmatory response.It is associated with poorer owz8 outcomesIn the advanced stages of
progressive disease, metabolism can change so that they lose wz8 weight even when they are gettin
g what is normally regarded as adequate nutrition z8and the body cannot compensate. This leads
to a condition call owz8 ed anorexia wz8 cachexia syndromnd a jowz8 dditional nutrition or supplement
ation is unlikely to help small amounts, nausea, anemia, weakness and fati
Serious weight loss may reduce quality 5jowz8 of life, impair treatment effectiv
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